Multicomponent diffusion of interacting, nonionic micelles with hydrophobic solutes

Growth of Mixed Nonionic Micelles

Static and quasielastic light-scattering measurements were utilized to investigate the shape, size, and polydispersity of mixed micelles composed of the nonionic surfactants dodecyl hexaoxyethylene glycol monoether (C12E6) and dodecyl octaoxyethylene glycol monoether (C12E8) in aqueous solutions. We determined the molecular weight and diffusion coefficient of these micelles and showed that they...

EVALUATION OF THE USE OF ANIONIC/ NONIONIC MIXED MICELLES IN REVERSED PHASE LIQUID CHROMATOGRAPHY OF CHLOROPHENOLS

The use of aqueous mixed micellar system consisting of sodium dodecyl sulfate (SDS) and polyoxyethylene (23) dodecanol (Brij-35) as the mobile phase in reversed-phase liquid chromatography was studied. A group of chlorophenols was used as the test mixture. Adding organic modifier to the system showed that the use of low concentrations of organic additives improves efficiency in SDS/Brij-35 mixe...

Diffusion of Surfactant Micelles

Nonionic Microemulsions as Solubilizers of Hydrophobic Drugs: Solubilization of Paclitaxel

The strategy using nonionic microemulsion as a solubilizer for hydrophobic drugs was studied and is demonstrated in this work. The aqueous phase behaviors of mixed nonionic surfactants with various oils at 37 °C are firstly constructed to give the optimal formulations of nonionic microemulsions with applications in the enhanced solubilization of the model hydrophobic drug, paclitaxel, at 37 °C....

Solvation of Ions in Aqueous Solutions of Hydrophobic Solutes

The self-diffusion of N a + , E t 4 N + and I in mixtures of water with n-propanol at 25 °C and with lert-butanol at 30 °C was measured as function of salt concentration and solvent composition. The limiting self-diffusion coefficients of the ions were used to compute the ionic radii. The influence of the composition of the solvent on the solvation of the ions is discussed. In aqueous solutions...